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Association Between Hypotension at Presentation and Postoperative Mortality in Emergency Laparotomy Patients

ETH-20260206-0118 تاريخ التقديم: Feb 06, 2026 / Submitted: Feb 06, 2026
قيمة الرسوم / Payment Amount
21,000.00 SDG
نوع البحث / Research Type
ورقة علمية / Research Paper
فترة الدراسة / Study Period
Feb 12, 2026 - Jun 12, 2026
Approved
السودان - الولاية الشمالية
وزارة الصحة
الادارة العامة للتخطيط والتنمية الصحية
إدارة البحوث
لجنة الموافقة الأخلاقية
طلب الموافقة الأخلاقية - Ethical Approval Request Form
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Ethical Approval Request Form
General Administration for Planning and Health Development
Research Department
Ethical Approval Committee
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رقم التسلسل
Serial Number
SER-20260206-0118
رقم الطلب
Request Number
ETH-20260206-0118
تاريخ تقديم الطلب
Date of Submission
2026-02-06

القسم الأول: معلومات الباحث / Principal Investigator Information

1. الاسم الكامل للباحث الرئيسي
Principal Investigator Full Name
Thoraya Salah Murtada Sidahmed
2. الجهة التي ينتمي إليها
Affiliation Type
جامعة / University: Alzaiem Alazhary University - Faculty of Medicine
Alzaiem Alazhary University - Faculty of Medicine
3. الوظيفة / اللقب العلمي
Job Title/Academic Degree
-
4. البريد الإلكتروني
Email Address
thorayagzzar@gmail.com
5. رقم الهاتف
Phone Number
0024911308727
المشرف / Supervisor
الاسم الكامل / Full Name
Dalal Nooreldein Mohamadin
البريد الإلكتروني / Email
-
الوظيفة / اللقب العلمي / Job Title
-
رقم الهاتف / Phone
-
القسم / المؤسسة / Department
-

القسم الثاني: تفاصيل الدراسة البحثية / Research Study Details

7. عنوان الدراسة
Study Title
Association Between Hypotension at Presentation and Postoperative Mortality in Emergency Laparotomy Patients
8. نوع البحث (يرجى التحديد)
Type of Research (Please select)
☐دكتوراه / PhD
☐ماجستير / Master's
☐بكالوريوس / Bachelor's
☐دبلوم عالي / Postgraduate Diploma
☐دبلوم وسيط / Intermediate Diploma
☑ورقة علمية / Research Paper
☐تقرير علمي / Scientific Report
☐أبحاث طبية / Medical Research
☐أخرى / Other
9. وصف مختصر للبحث
Brief Description of Research
Background Emergency laparotomy is a high-risk surgical procedure with significant postoperative mortality. Patients often present with hemodynamic instability, especially hypotension, due to sepsis, hemorrhage, or perforated viscus. Preoperative hypotension reflects physiological derangement and poor tissue perfusion, which may contribute to adverse outcomes. International studies have confirmed its prognostic value, yet data from Sudanese hospitals are limited. Problem Statement Postoperative mortality following emergency laparotomy remains unacceptably high in Sudan. However, the predictive role of hypotension at presentation has not been adequately investigated, limiting early risk stratification and resuscitation strategies. Justification Identifying hypotension as a predictor of mortality will enable early triage, aggressive resuscitation, and tailored perioperative management for high-risk patients. This can help reduce mortality and guide clinical decision-making in emergency settings. General Objective To determine the association between hypotension at presentation and postoperative mortality in emergency laparotomy patients. Specific Objectives 1. To determine the prevalence of hypotension among emergency laparotomy patients. 2. To determine postoperative mortality rate among these patients. 3. To assess the association between preoperative hypotension and postoperative mortality. 4. To identify other factors associated with postoperative mortality

القسم الثالث: الجوانب الأخلاقية / Ethical Considerations

10. طريقة الحصول على الموافقة من المشاركين
Method of Obtaining Consent from Participants
☑مكتوبة / Written
☐شفهية / Verbal
☐غير مطبقة / Not Applicable
☐ضمنية / Implied
☐إعفاء / Waiver
يرجى إرفاق نموذج الموافقة / Please attach consent form
11. آلية الحفاظ على سرية المعلومات
Confidentiality Measures
We will obtain written informed consent from every patient before any data is collected. All records will be anonymized by removing names and using unique ID numbers instead, ensuring that no individual can be identified in the final report. Access to the data will be strictly limited to the research team, and all personal information will remain completely confidential.
12. مدى المخاطر على المشاركين
Risk Level to Participants
☐لا توجد / None
☑طفيفة / Minor
☐متوسطة / Moderate
☐عالية / High
يرجى توضيح أي مخاطر محتملة وخطة التعامل معها / Please describe any potential risks and mitigation:
This study poses no significant risk to participants. It is an observational study that relies on routine clinical data
13. الفوائد المحتملة للمشاركين أو المجتمع
Potential Benefits to Participants or Society
The data will provide local evidence to support clinical decision-making, helping surgeons and anesthesiologists balance the urgency of surgery with the need for preoperative stabilization.
14. هل تشمل الدراسة فئات ضعيفة؟
Does the study involve vulnerable groups?
☐الأطفال / Children
☐النساء الحوامل / Pregnant Women
☐اللاجئون/النازحون / Refugees/Displaced
☐ذوو الإعاقة / People with Disabilities
☐أخرى / Other:

القسم الرابع: قائمة المرفقات المطلوبة / Required Attachments

نسخة من المقترح البحثي الكامل
Full Research Proposal
أدوات جمع البيانات
Data Collection Tools
خطاب تسهيل من الجامعة
University Facilitation Letter

القسم الخامس: الإقرار والتوقيع / Acknowledgment and Signature

أُقر أنا الموقع أدناه بأن جميع المعلومات الواردة في هذه الاستمارة صحيحة وكاملة، وأتعهد بعدم البدء في أي جزء من الدراسة قبل الحصول على الموافقة الأخلاقية الرسمية، والالتزام بجميع الإرشادات والمعايير الأخلاقية المعتمدة من قبل لجنة الموافقة الأخلاقية.
I, the undersigned, acknowledge that all information provided in this form is accurate and complete, and I agree not to begin any part of the study before receiving official ethical approval, and to comply with all ethical guidelines and standards approved by the Ethical Approval Committee.
اسم الباحث الرئيسي / Principal Investigator Name
Thoraya Salah Murtada Sidahmed
التوقيع / Signature
_______________________
التاريخ / Date
2026-02-06

معلومات الباحث / Researcher Information

T

Thoraya Salah Murtada Sidahmed

thorayagzzar@gmail.com

0024911308727

جامعة: Alzaiem Alazhary University الكلية: Faculty of Medicine

Dongola Specialized Hospital

اسم المؤسسة التي سيتم فيها عمل البحث / Name of the institution where the research will be conducted

معلومات الدراسة / Study Information

ورقة علمية / Research Paper

messages.degree_research_paper - messages.degree_research_paper

21,000.00 SDG

Background Emergency laparotomy is a high-risk surgical procedure with significant postoperative mortality. Patients often present with hemodynamic instability, especially hypotension, due to sepsis, hemorrhage, or perforated viscus. Preoperative hypotension reflects physiological derangement and poor tissue perfusion, which may contribute to adverse outcomes. International studies have confirmed its prognostic value, yet data from Sudanese hospitals are limited. Problem Statement Postoperative mortality following emergency laparotomy remains unacceptably high in Sudan. However, the predictive role of hypotension at presentation has not been adequately investigated, limiting early risk stratification and resuscitation strategies. Justification Identifying hypotension as a predictor of mortality will enable early triage, aggressive resuscitation, and tailored perioperative management for high-risk patients. This can help reduce mortality and guide clinical decision-making in emergency settings. General Objective To determine the association between hypotension at presentation and postoperative mortality in emergency laparotomy patients. Specific Objectives 1. To determine the prevalence of hypotension among emergency laparotomy patients. 2. To determine postoperative mortality rate among these patients. 3. To assess the association between preoperative hypotension and postoperative mortality. 4. To identify other factors associated with postoperative mortality

Feb 12, 2026 - Jun 12, 2026

Feb 15, 2026 - Mar 15, 2026

الاعتبارات الأخلاقية / Ethical Considerations

Written

مخاطر منخفضة - Low Risk

We will obtain written informed consent from every patient before any data is collected. All records will be anonymized by removing names and using unique ID numbers instead, ensuring that no individual can be identified in the final report. Access to the data will be strictly limited to the research team, and all personal information will remain completely confidential.

This study poses no significant risk to participants. It is an observational study that relies on routine clinical data

The data will provide local evidence to support clinical decision-making, helping surgeons and anesthesiologists balance the urgency of surgery with the need for preoperative stabilization.