أبحاث طبية / Medical Research

**Title:** Indications and Outcomes of Pars Plana Vitrectomy (PPV) in a Tertiary Eye Center ### **Background** Pars plana vitrectomy (PPV) is a microsurgical procedure widely used to treat vitreoretinal diseases such as vitreous hemorrhage, retinal detachment, epiretinal membrane, macular hole, and diabetic retinopathy complications. Advances in surgical techniques and instrumentation have improved outcomes. However, surgical success depends on indications, disease duration, patient characteristics, and surgeon expertise. Local data on PPV indications and outcomes in Sudan are limited. ### **Problem** There is insufficient local information on the common indications, visual outcomes, anatomical success, and complication rates for PPV in tertiary eye centers, which is essential for planning, optimizing care, and resource allocation. ### **Objectives** * **General:** Evaluate indications and outcomes of PPV at Aljawareh Eye Hospital. * **Specific:** * Identify the most common indications for PPV * Assess postoperative visual acuity outcomes * Evaluate anatomical success rates (retinal reattachment, media clarity) * Identify intraoperative and postoperative complications ### **Methodology** * **Design:** Hospital-based prospective descriptive study * **Location:** Aljawareh Eye Hospital, Dongola, Sudan * **Population:** All patients undergoing PPV during the study period * **Exclusions:** Incomplete records, lost to follow-up * **Sampling:** Total coverage of all eligible cases * **Data Collection:** Patient records, surgical logs, OCT/imaging; variables include demographics, indications, duration of symptoms, surgical details (tamponade, combined procedures), pre- and postoperative VA, anatomical outcomes, and complications (cataract, elevated IOP, endophthalmitis, re-detachment) * **Analysis:** SPSS 26.0; descriptive statistics (frequencies, mean ± SD), paired t-tests for VA, chi-square and regression for predictors; significance p < 0.05 ### **Expected Outcomes** * Vitreous hemorrhage and retinal detachment as the most common indications * Significant improvement in visual acuity * High anatomical success rates * Acceptable complication rates comparable to international standards ### **Ethics** * Approval from Ministry of Health, Northern State, Sudan * Confidentiality of patient data; informed consent for prospective cases ### **Limitations** * Short follow-up * Missing data or loss to follow-up ### **Timeline** * Proposal approval: 1 month * Data collection: 2–4 months * Data analysis: 1 month * Report writing: 1 month ### **Budget** * Data collection materials * Printing and documentation * Statistical software

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